Product overview
Small-dose respule packaging requires both accurate filling and a reliable seal because the product is commonly a sensitive pharmaceutical liquid and the container volume is very small.
The Automatic Respules Filling And Ultrasonic Sealing Machine combines peristaltic pump filling with ultrasonic sealing of pre-formed open-top respules.
Technogen Enterprise is an Automatic Respules Filling And Ultrasonic Sealing Machine Manufacturer and Supplier for Tanzania, serving pharmaceutical liquid packaging, R&D and pilot-production applications.
The machine handles 2–5 ml fills with stated accuracy of approximately ±1%, depending upon product viscosity.
Pre-formed LDPE and LLDPE respules are filled through pharmaceutical-grade silicone tubing and then automatically sealed through the ultrasonic station. Pasted text(3)
PLC-HMI control provides process parameter adjustment, recipe management and cycle monitoring.
Working principle
Pre-formed respules are introduced into the machine.
The container reaches the filling station.
The No Respule–No Fill logic confirms container presence.
A peristaltic pump dispenses the programmed 2–5 ml quantity.
The filled respule transfers to the ultrasonic sealing station.
Ultrasonic energy seals the container opening.
The PLC controls sealing time and energy settings.
Completed respules exit the sealing cycle for downstream handling.
Salient features
- Automatic Fill & Seal Cycle : Integrates respule filling and ultrasonic sealing.
- Peristaltic Pump Filling : Provides controlled small-volume liquid dispensing.
- LDPE / LLDPE Compatibility : Designed for pre-formed respules.
- PLC Control : Coordinates filling and sealing sequences.
- Touchscreen HMI : Allows process settings and recipe selection.
- SS 316L Product Contact Parts : Used in specified product-contact areas.
- SS 304 Machine Structure : External frame and panels use SS 304.
- Low Noise Operation : Noise level is specified below 70 dB.
- Recipe Management : Supports operating settings for different compatible respule formats.
Safety & interlocks
- No Respule–No Fill : Prevents liquid dispensing without a container.
Applications & industries
PharmaceuticalApplication items
- Inhalation Solutions : Filling of compatible pharmaceutical respiratory liquids.
- Sterile Liquids : Packaging of compatible sensitive liquid formulations.
- Respiratory Drugs : Respule filling for compatible respiratory products.
- Diagnostic Samples : Filling and sealing of compatible diagnostic liquids.
- R&D Batches : Suitable for formulation-development quantities.
- Pilot Production : Supports controlled pharmaceutical pilot-scale production.
Technical specifications
| Parameter | TGRFS-15 | TGRFS-50 |
|---|---|---|
| Filling Range | 2 – 5 ml | 2–5 ml |
| Filling Accuracy | ± 1% | ± 1% |
| Output (Approx.) | 5 – 12 respules/min depending upon human efficiency | 45–50 respules/min depending upon human efficiency |
| Number of Filling Heads | 1 (Single Head) | 5 |
| Pump Type | Peristaltic Pump | Peristaltic Pump |
| Sealing System | Ultrasonic Sealing | Ultrasonic Sealing |
| Respule Type | LDPE / LLDPE | LDPE / LLDPE |
| Power Supply | 230 V AC, 50 Hz, Single Phase | 230 V AC, 50 Hz, Single Phase |
| Air Supply | 6 bar Clean Dry Air | 6 bar Clean Dry Air |
| Control System | PLC + HMI | PLC + HMI |
| Construction | GMP Model, SS 304 / SS 316L | GMP Model, SS 304 / SS 316L |
| Noise Level | 70 dB | 70 dB |
Product gallery

Automatic Respules Filling And Ultrasonic Sealing Machine for Tanzania production
For manufacturers in Tanzania, Automatic Respules Filling And Ultrasonic Sealing Machine should be evaluated against the actual product, pack format, production schedule and operating environment. Automatic pharmaceutical machine for precision peristaltic filling and ultrasonic sealing of pre-formed LDPE and LLDPE respules in 2–5 ml fill volumes. The selected arrangement must suit both routine output and the changeovers expected during normal production.
Operating and product considerations
The dosing method is selected from the product behaviour and required fill range. Viscosity, density, foaming, suspended particles, powder flow or dosage form can influence the hopper, pump, auger, nozzle and container-handling arrangement. Product trials or representative samples reduce uncertainty before configuration.
Planning the complete production line
Tanzanian manufacturers should also define the container infeed, closure process, cleaning expectation and downstream labelling or secondary packaging. Reviewing these interfaces together helps establish a balanced line and prevents one machine from limiting the practical output of the complete process.
Information required for machine selection
- Product viscosity, density, foaming behaviour and suspended particles
- Minimum and maximum fill quantity with acceptable tolerance
- Container material, dimensions, neck opening and target output
Enquiries are supported for projects in Dar es Salaam, Dodoma, Mwanza, Arusha, Morogoro and other Tanzanian industrial locations. The final model, construction, output, documentation and support scope are confirmed in the commercial and technical offer.


